InsiderSource

PERCEPTIVE ADVISORS LLC

Director, 10% Owner · SEC CIK 1224962
Insider at SLDB Solid Biosciences Inc. MGTX MeiraGTx Holdings plc ATHA Athira Pharma, Inc. LYRA Lyra Therapeutics, Inc. ADGM Adagio Medical Holdings, Inc. OBIO Orchestra BioMed Holdings, Inc. ACRV Acrivon Therapeutics, Inc. ALDX Aldeyra Therapeutics, Inc. NAUT Nautilus Biotechnology, Inc. CERE Cerevel Therapeutics Holdings, Inc. LIAN LianBio ATXS Astria Therapeutics, Inc. VRCA Verrica Pharmaceuticals Inc. CRGX CARGO Therapeutics, Inc. SLNO SOLENO THERAPEUTICS INC
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Buy track record

How this insider's open-market purchases have performed
53%
of buys now in profit
18 up · 16 down
Avg return since buy+14.4%
Median return+39.2%
Best trade+139.8%
Worst trade−92.2%
Buys scored34 (+9 n/a)
Average return by holding period — separates good entry timing from riding one long winner
After 1 month −7.0% 24% won · 34 trades
After 3 months +16.5% 53% won · 34 trades
After 6 months +38.9% 91% won · 34 trades
After 12 months +9.4% 55% won · 33 trades
DateCompany90d trendBuy priceValueΔOwn1M3M6M12MTo date
Aug 1, 2025 OBIO $3 $1.93M +15% +12.3% +61.9% +64.8% — +68.0%
Feb 19, 2025 SLDB $4 $20.15M +73% −25.5% −55.2% −10.4% −9.1% +10.4%
Aug 12, 2024 MGTX $4 $5M +11% +4.3% +66.5% +61.0% +100.5% +139.8%
Apr 11, 2024 ACRV $9 $20M +78% −8.7% −14.9% −21.5% −82.6% −84.1%
Apr 5, 2024 ALDX $5 $178.8K +0.4% −12.7% −32.4% +11.9% −58.7% −62.7%
Apr 4, 2024 ALDX $5 $655.1K +1.5% −12.1% −31.9% +14.0% −59.7% −62.4%
Apr 3, 2024 ALDX $4 $1.27M +3.5% +0.2% −22.9% +26.0% −65.8% −57.6%
Apr 2, 2024 ALDX $3 $640K +2.2% +18.6% −8.5% +49.3% +50.0% −50.4%
Apr 1, 2024 ALDX $3 $27.2K +0.1% +28.4% −0.6% +61.8% +67.4% −46.2%
Jan 11, 2024 SLDB $6 $18.86M +100% +4.8% +38.4% +6.4% −57.0% −7.3%
Dec 29, 2023 VRCA $7 $838.2K +1.7% −18.2% −19.1% +8.6% −90.4% −92.2%
Dec 28, 2023 VRCA $7 $892.9K +1.8% −17.8% −18.8% +0.0% −90.4% −92.1%
Dec 27, 2023 VRCA $7 $574K +1.2% −16.2% −21.0% +1.0% −90.4% −92.0%
Dec 26, 2023 VRCA $6 $354.7K +0.8% −10.9% −18.2% +8.5% −90.0% −91.2%
Dec 22, 2023 VRCA $7 $1.67M +3.9% −14.5% −26.5% +4.3% −89.7% −91.6%
Dec 21, 2023 VRCA $6 $1.23M +3.2% −9.0% −21.2% +16.2% −89.0% −91.1%
Dec 19, 2023 VRCA $5 $1.48M +4.6% +6.3% −14.7% +29.7% −87.8% −89.7%
Dec 18, 2023 VRCA $5 $2.47M +8.2% +3.6% −14.6% +43.9% −88.4% −89.7%
Dec 15, 2023 VRCA $6 $2.99M +9.9% −7.6% −21.2% +34.0% −88.2% −90.6%
Sep 28, 2023 SLNO $20 $5M +8.9% −16.1% +43.1% +55.1% +83.0% +92.1%
Sep 26, 2023 SLNO $8 $43.6K +0.3% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $8 $113.6K +0.6% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $10 $51.6K +0.2% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $11 $418.9K +1.7% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $12 $919.3K +3.4% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $13 $550K +1.8% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $14 $424.7K +1.3% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $15 $48.6K +0.1% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $16 $444.3K +1.1% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $17 $1.3M +3.1% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $18 $961.1K +2.1% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $19 $1.69M +3.4% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $20 $2.36M +4.4% −10.5% +49.5% +61.2% +82.0% +97.8%
Sep 26, 2023 SLNO $21 $775.7K +1.3% −10.5% +49.5% +61.2% +82.0% +97.8%
How this is calculated. We score only open-market purchases (SEC code P) — the buys that carry real signal. Each trade's return is measured from the adjusted closing price on the purchase date to the latest close, accounting for stock splits and dividends. The 1M/3M/6M/12M columns show the same trade's return after each fixed holding period; a dash means that horizon hasn't elapsed yet or isn't priceable. Sales are excluded because insiders sell for many routine reasons. With only 34 scored trades, treat this as a small sample, not a verdict.
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Open-market buys
$164.37M
43 trades
Open-market sells
$13.57M
20 trades
Net flow
+$150.8M
Net buying
Total filings
72
transactions shown

Full transaction history

All Form 4 activity across every company, newest first
View on SEC EDGAR ↗
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OBIO
Orchestra BioMed Holdings, Inc.
Buy PERCEPTIVE ADVISORS LLC · 10% Owner · Open-market purchase · filed Aug 5, 2025 ΔOwn +15%

Perceptive Advisors Llc, OBIO's 10% owner, spent $1.93M of their own money on 700,000 shares at $3, growing their stake 15%.

+$1.93M
700,000 sh @ $3
SLDB
Solid Biosciences Inc.
Buy PERCEPTIVE ADVISORS LLC · Director, 10% Owner · Open-market purchase · filed Feb 21, 2025 ΔOwn +73%

Perceptive Advisors Llc, SLDB's 10% owner, spent $20.15M of their own money on 5M shares at $4, growing their stake 73%.

+$20.15M
5M sh @ $4
MGTX
MeiraGTx Holdings plc
Buy PERCEPTIVE ADVISORS LLC · Director, 10% Owner · Open-market purchase · filed Aug 14, 2024 ΔOwn +11%

Perceptive Advisors Llc, MGTX's 10% owner, spent $5M of their own money on 1.25M shares at $4, growing their stake 11%.

+$5M
1.25M sh @ $4
ACRV
Acrivon Therapeutics, Inc.
Buy PERCEPTIVE ADVISORS LLC · 10% Owner · Open-market purchase · filed Apr 15, 2024 ΔOwn +78%

Perceptive Advisors Llc, ACRV's 10% owner, spent $20M of their own money on 2.35M shares at $9, growing their stake 78%.

+$20M
2.35M sh @ $9
ALDX
Aldeyra Therapeutics, Inc.
Buy PERCEPTIVE ADVISORS LLC · 10% Owner · Open-market purchase · filed Apr 8, 2024 ΔOwn +0.4%

Perceptive Advisors Llc, ALDX's 10% owner, spent $178.8K of their own money on 37,712 shares at $5.

+$178.8K
37,712 sh @ $5
ALDX
Aldeyra Therapeutics, Inc.
Buy PERCEPTIVE ADVISORS LLC · 10% Owner · Open-market purchase · filed Apr 8, 2024 ΔOwn +1.5%

Perceptive Advisors Llc, ALDX's 10% owner, spent $655.1K of their own money on 140,281 shares at $5, growing their stake 2%.

+$655.1K
140,281 sh @ $5
ALDX
Aldeyra Therapeutics, Inc.
Buy PERCEPTIVE ADVISORS LLC · 10% Owner · Open-market purchase · filed Apr 3, 2024 ΔOwn +3.5%

Perceptive Advisors Llc, ALDX's 10% owner, spent $1.27M of their own money on 309,847 shares at $4, growing their stake 4%.

+$1.27M
309,847 sh @ $4

Frequently asked questions

How is PERCEPTIVE ADVISORS LLC's win rate calculated?

We take every open-market purchase (SEC code P) we can match to a stock price, then compare the split- and dividend-adjusted price on the purchase date to the most recent close. The win rate is the share of those buys currently trading above the purchase price. Sales and share grants are not scored.

Why are some buys not included in the score?

A purchase is excluded if we can't price it — for example if the ticker is missing from the filing, the company has been delisted, or the security isn't a common stock we can match to market data. Excluded counts are shown next to the scored total.

What do the 1M / 3M / 6M / 12M columns mean?

They show each purchase's return after a fixed holding period — one, three, six, and twelve months from the buy date — using split- and dividend-adjusted prices. This separates good entry timing from simply holding a long-running winner. A dash means that horizon hasn't elapsed yet for that trade, or the stock couldn't be priced at that date.

Does a high win rate mean I should copy this insider?

No. Past performance does not predict future results, sample sizes are often small, and an insider's edge in their own company doesn't transfer to yours. This is context, not a recommendation. InsiderSource is not investment advice.

Where does this data come from?

Trades come from PERCEPTIVE ADVISORS LLC's SEC Form 4 filings on EDGAR. Prices come from public market data and are split/dividend-adjusted. Always verify against the original filings before acting.