PRME

Prime Medicine, Inc.

SEC CIK 1894562
$2.78 −20.1% · 90 days
90-day buys
$0
0 open-market
90-day sells
$0
0 open-market
Net insider flow
+$0
Net buying
Filings shown
40
Most recent
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At a glance

Insiders at PRME have made no open-market trades in the last 90 days — the activity below is grants, option exercises, and other routine filings.

Largest recent trade: Arch Venture Partners X, Llc, PRME's 10% owner, spent $20M of their own money on 3.2M shares at $6, opening a brand-new position.

Most active filer: Gv 2019 Gp, L.l.c., with 34 transactions among the recent filings shown.

Insider transaction history

Form 4 filings for PRME, newest first
View on SEC EDGAR ↗
PRME
Buy GV 2021 GP, L.L.C. · 10% Owner · Open-market purchase · filed Aug 5, 2025 ΔOwn +85%

Gv 2021 Gp, L.l.c., PRME's 10% owner, spent $4.95M of their own money on 1.5M shares at $3, growing their stake 85%.

+$4.95M
1.5M sh @ $3
PRME
Buy NELSEN ROBERT · Director, 10% Owner · Open-market purchase · filed Aug 1, 2025 ΔOwn +95%

Nelsen Robert, PRME's 10% owner, spent $10M of their own money on 3.03M shares at $3, growing their stake 95%.

+$10M
3.03M sh @ $3
PRME
Buy ARCH Venture Partners XII, LLC · 10% Owner · Open-market purchase · filed Aug 1, 2025 ΔOwn +95%

Arch Venture Partners Xii, Llc, PRME's 10% owner, spent $10M of their own money on 3.03M shares at $3, growing their stake 95%.

+$10M
3.03M sh @ $3
PRME
Buy ARCH Venture Partners X, LLC · 10% Owner · Open-market purchase · filed Aug 1, 2025 ΔOwn +95%

Arch Venture Partners X, Llc, PRME's 10% owner, spent $10M of their own money on 3.03M shares at $3, growing their stake 95%.

+$10M
3.03M sh @ $3
PRME
Buy ARCH Venture Partners X, LLC · 10% Owner · Open-market purchase · filed Feb 20, 2024 ΔOwn NEW

Arch Venture Partners X, Llc, PRME's 10% owner, spent $20M of their own money on 3.2M shares at $6, opening a brand-new position.

+$20M
3.2M sh @ $6
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PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 22, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $284.5K of PRME, trimming their stake 100%.

−$284.5K
19,003 sh @ $15
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 22, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $563.2K of PRME, trimming their stake 100%.

−$563.2K
37,405 sh @ $15
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 20, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $98.1K of PRME, trimming their stake 100%.

−$98.1K
6,532 sh @ $15
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 20, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $994.3K of PRME, trimming their stake 100%.

−$994.3K
66,659 sh @ $15
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 15, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $430.7K of PRME, trimming their stake 100%.

−$430.7K
28,960 sh @ $15
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 15, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $425.1K of PRME, trimming their stake 100%.

−$425.1K
28,100 sh @ $15
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 13, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $240.2K of PRME, trimming their stake 100%.

−$240.2K
16,031 sh @ $15
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 13, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $227K of PRME, trimming their stake 100%.

−$227K
15,672 sh @ $14
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 9, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $78.7K of PRME, trimming their stake 100%.

−$78.7K
5,000 sh @ $16
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 9, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $253.9K of PRME, trimming their stake 100%.

−$253.9K
15,000 sh @ $17
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 7, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $510.2K of PRME, trimming their stake 100%.

−$510.2K
29,975 sh @ $17
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 7, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $374.6K of PRME, trimming their stake 100%.

−$374.6K
22,434 sh @ $17
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 2, 2023 ΔOwn −99%

Gv 2019 Gp, L.l.c. sold $642.2K of PRME, trimming their stake 99%.

−$642.2K
44,752 sh @ $14
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 2, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $6.9K of PRME, trimming their stake 100%.

−$6.9K
471 sh @ $15
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed Jun 2, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $227K of PRME, trimming their stake 100%.

−$227K
16,633 sh @ $14
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed May 31, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $230.2K of PRME, trimming their stake 100%.

−$230.2K
16,805 sh @ $14
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed May 31, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $172.6K of PRME, trimming their stake 100%.

−$172.6K
12,602 sh @ $14
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed May 26, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $310K of PRME, trimming their stake 100%.

−$310K
23,161 sh @ $13
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed May 26, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $107.9K of PRME, trimming their stake 100%.

−$107.9K
7,900 sh @ $14
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed May 24, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $647.6K of PRME, trimming their stake 100%.

−$647.6K
43,939 sh @ $15
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed May 24, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $1.24M of PRME, trimming their stake 100%.

−$1.24M
87,922 sh @ $14
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed May 22, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $877.1K of PRME, trimming their stake 100%.

−$877.1K
63,212 sh @ $14
PRME
Sell GV 2019 GP, L.L.C. · 10% Owner · Open-market sale · filed May 22, 2023 ΔOwn −100%

Gv 2019 Gp, L.l.c. sold $183.2K of PRME, trimming their stake 100%.

−$183.2K
14,022 sh @ $13
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About PRME insider activity

This page tracks every recent Form 4 filed for Prime Medicine, Inc. with the U.S. Securities and Exchange Commission. Form 4 is the disclosure that company insiders — officers, directors, and holders of more than 10% of the stock — must file within two business days of buying or selling shares.

The summary above nets open-market purchases against open-market sales over the trailing 90 days. Open-market trades (codes P and S) tend to carry the most signal because they reflect a deliberate choice to put money in or take it out, as opposed to routine grants, option exercises, or tax-withholding events. Use the badges on each row to tell them apart, and always confirm details against the original filing before drawing conclusions.

Frequently asked questions

How often is PRME insider data updated?

Continuously. We read from SEC EDGAR, so new Form 4 filings for Prime Medicine, Inc. usually appear here within minutes of being accepted by the SEC.

What does "net insider flow" mean?

It is the total dollar value of open-market insider purchases minus open-market sales over the last 90 days. A positive number (green) means insiders bought more than they sold; a negative number (red) means the reverse.

Why do some rows show grants or option exercises instead of buys?

Insiders receive stock through compensation as well as buying it outright. Form 4 captures all of these. We label each transaction by its SEC code so you can focus on open-market activity if you prefer.

Is this investment advice?

No. InsiderSource presents public filing data for informational purposes only. Insider activity is one of many factors to consider and is never a recommendation to buy or sell.